國家衛生研究院 NHRI:Item 3990099045/13864

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Title:	Microfluidic technology for multiple single-cell capture
Authors:	He, CK;Hsu, CH
Contributors:	Institute of Biomedical Engineering and Nanomedicine
Abstract:	Microfluidic devices are widely used in single-cell capture and for pairing single cells or groups of cells for cell–cell interaction analysis; these advances have improved drug screening and cell signal transduction analysis. The complex in vivo environment involves interactions between two cells and among multiple cells of the same or different phenotypes. This study reviewed the core principles and performance of several microfluidic multiple- and single-cell capture methods, namely, the microwell, valve, trap, and droplet methods. The advantages and disadvantages of the methods were compared, and suggestions regarding their application to multiple-cell capture were provided. The results may serve as a reference for research on microfluidic multiple single-cell coculture technology.
Date:	2021-11-08
Relation:	Biomicrofluidics. 2021 Nov 8;15(6):Article number 061501.
Link to:	http://dx.doi.org/10.1063/5.0057685
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1932-1058&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000717531800003
Cited Times(Scopus):	https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85119063211
Appears in Collections:	[Chia-Hsien Hsu] Periodical Articles

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