國家衛生研究院 NHRI:Item 3990099045/13703
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12145/12927 (94%)
造訪人次 : 857761      線上人數 : 798
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/13703


    題名: Data analysis of the risks of type 2 diabetes mellitus complications before death using a data‐driven modelling approach: Methodologies and challenges in prolonged diseases
    作者: Lin, MY;Liu, JS;Huang, TY;Wu, PH;Chiu, YW;Kang, Y;Hsu, CC;Hwang, SJ;Luh, H
    貢獻者: Institute of Population Health Sciences
    摘要: (1) Background: A disease prediction model derived from real‐world data is an important tool for managing type 2 diabetes mellitus (T2D). However, an appropriate prediction model for the Asian T2D population has not yet been developed. Hence, this study described construction details of the T2D Holistic Care model via estimating the probability of diabetes‐related complications and the time‐to‐occurrence from a population‐based database. (2) Methods: The model was based on the database of a Taiwan pay‐for‐performance reimbursement scheme for T2D between November 2002 and July 2017. A nonhomogeneous Markov model was applied to simulate multi-state (7 main complications and death) transition probability after considering the sequential and repeated difficulties. (3) Results: The Markov model was constructed based on clinical care information from 163,452 patients with T2D, with a mean follow‐up time of 5.5 years. After simulating a cohort of 100,000 hypothetical patients over a 10‐year time horizon based on selected patient characteristics at baseline, a good predicted complication and mortality rates with a small range of ab-solute error (0.3–3.2%) were validated in the original cohort. Better and optimal predictabilities were further confirmed compared to the UKPDS Outcomes model and applied the model to other Asian populations, respectively. (4) Contribution: The study provides well‐elucidated evidence to apply real‐world data to the estimation of the occurrence and time point of major diabetes‐related complications over a patient’s lifetime. Further applications in health decision science are encouraged.
    日期: 2021-08-12
    關聯: Information. 2021 Aug 12;12(8):Article number 326.
    Link to: http://dx.doi.org/10.3390/info12080326
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85113715762
    顯示於類別:[許志成] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    SCP85113715762.pdf5626KbAdobe PDF179檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋