國家衛生研究院 NHRI:Item 3990099045/13227
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/13227


    Title: Role of electrocardiographic early repolarization pattern in long-term outcomes of a community-based middle-aged and geriatric ambulatory population: A prospective cohort study
    Authors: Juang, JMJ;Huang, YJ;Chang, IS;Chen, CYJ;Wu, IC;Hsu, CC;Chen, TY;Tseng, WT;Yeh, SFS;Hsiung, CA
    Contributors: Institute of Population Health Sciences;National Institute of Cancer Research
    Abstract: In some studies, electrocardiographic early repolarization pattern (ERP) has been associated with an increased risk of death from cardiac causes. However, little is known about the prognostic significance of ERP in the middle-aged and geriatric general populations. We investigated the prevalence and long-term prognostic significance of early repolarization pattern (ERP) on electrocardiograms (ECGs) in the Healthy Aging Longitudinal Study (HALST) cohort of 4615 middle-aged and geriatric community-dwelling Han Chinese adults from Taiwan. The study subjects were followed-up for 9522 months. A positive ERP of >= 0.1 mV was observed in 889 (19.3%) of the subjects. Kaplan-Meier survival curve analysis showed that ERP was not associated with all-cause and cardiovascular mortality (log-rank test, P=0.13 and 0.84, respectively). Cox regression analysis after adjusting for covariables revealed that age, blood pressure, smoking, diabetes, stroke, chronic kidney disease, and corrected QT interval (QTc) were associated with increased risk of all-cause mortality (P<0.05). Age, and stroke were risk factors associated with increased risk of cardiovascular mortality (P<0.05). However, ERP alone was not associated with all-cause or cardiovascular mortality. These findings show that ERP is common in the middle-aged and geriatric Han-Chinese individuals from the HALST cohort and is not associated with all-cause or cardiovascular mortality.
    Date: 2020-12
    Relation: Aging-Us. 2020 Dec;12(24):26140-26187.
    Link to: https://doi.org/10.18632/aging.202369
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1945-4589&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000605579300002
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85098979899
    Appears in Collections:[Chao A. Hsiung] Periodical Articles
    [Chih-Cheng Hsu] Periodical Articles
    [I-Chien Wu] Periodical Articles
    [I-Shou Chang] Periodical Articles

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