國家衛生研究院 NHRI:Item 3990099045/12781
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    题名: Investigating the health disparities in the association between lifestyle behaviors and the risk of head and neck cancer
    作者: Hsiao, JR;Huang, CC;Ou, CY;Chang, CC;Lee, WT;Tsai, ST;Huang, JS;Chen, KC;Lai, YH;Wu, YH;Hsueh, WT;Wu, SY;Yen, CJ;Chang, JY;Lin, CL;Weng, YL;Yang, HC;Chen, YS;Chang, JS
    贡献者: National Institute of Cancer Research
    摘要: Many studies have reported a positive association between lower socioeconomic status (SES) and higher head and neck cancer (HNC) risk. Fewer studies have examined the impact of SES on the association between alcohol or cigarette use and HNC risk. The current case-control study (1,104 HNC cases and 1,363 controls) investigated the influence of education, a SES indicator, on the association between HNC and the use of alcohol, cigarettes, or betel quids in Taiwan, a country with universal health care. Our results showed a larger increase in HNC risk associated with alcohol among those with lower educational level (odds ratio (OR) = 2.07, 95% confidence interval (CI): 1.53-2.80) than those with higher educational level (OR = 1.38, 95% CI: 1.04-1.85) (heterogeneity-p = 0.03). Educational level had an influence on the association between alcohol use and HNC risk among those with genetic susceptibility (ALDH2-deficient) to the carcinogenic effect of alcohol. The association between cigarette or betel quid use and HNC risk was similar between the high and the low educational groups. National policies and social interventions have led to the decline in the prevalences of cigarette and betel quid users in Taiwan. In contrast, due the lack of adequate alcohol control policies, alcohol consumption in Taiwan has continued to rise. A higher impact of alcohol on HNC risk among lower SES individuals even with universal health care could be the result of insufficient alcohol control policies in Taiwan.
    日期: 2020-08
    關聯: Cancer Science. 2020 Aug;111(8):2974-2986.
    Link to: http://dx.doi.org/10.1111/cas.14530
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1347-9032&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000551189100001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85088397936
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