國家衛生研究院 NHRI:Item 3990099045/12598
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    题名: Formability of Fe-doped bioglass scaffold via selective laser sintering
    作者: Chiu, KY;Chen, KK;Wang, YH;Lin, FH;Huang, JY
    贡献者: Institute of Biomedical Engineering and Nanomedicine
    摘要: Because of its outstanding characteristics, bioglass is considered a potential bone substitute; however, it is difficult to be fabricated into a scaffold because of insufficient strength. Although there are several methods for producing a three-dimensional ceramic scaffold, most of these methods cannot completely mimic the bone structure. In this study, a bioglass scaffold was fabricated through selective laser sintering (SLS) with the addition of the iron element that could ascend the laser absorption rate with the improvement of the formability and mechanical strength of scaffolds. As a result, the laser absorption proficiency improved with an increase in the amount of iron added; a competent bioglass scaffold could be successfully manufactured with a 5% iron element addition at the energy density of 2.5 cal/cm2 (3-W power and 120 mm/s scan speed). In a comparison of scaffolds sintered with various parameters of the heat treatment, scaffolds that had favourable mechanical strength and cell survival rate could be acquired after sintering at 1100 °C. According to the result of the present study, a competent biocompatible bioglass scaffold could be obtained using the SLS process with the addition of the iron element and suitable post-processing parameters.
    日期: 2020-07
    關聯: Ceramics International. 2020 Jul;46(10 Pt.B):16510-16517.
    Link to: http://dx.doi.org/10.1016/j.ceramint.2020.03.216
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0272-8842&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000533512000090
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85082517214
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