國家衛生研究院 NHRI:Item 3990099045/12175
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/12175


    Title: Incidence of retinal vein occlusion with long-term exposure to ambient air pollution
    Authors: Zhang, HW;Lin, CW;Kok, VC;Tseng, CH;Lin, YP;Li, TC;Sung, FC;Wen, CP;Hsiung, CA;Hsu, CY
    Contributors: Institute of Population Health Sciences
    Abstract: This study aimed to investigate whether long-term exposure to airborne hydrocarbons, including volatile organic compounds, increases the risk of developing retinal vein occlusion (RVO) among the population of Taiwan. A retrospective cohort study involving 855,297 people was conducted. Cox proportional hazards regression analysis fitted the multiple pollutant models for two targeted pollutants, including total hydrocarbons (THC), nonmethane hydrocarbons (NMHC) were used, and the risk of RVO was estimated. The chi-squared test and one-way analysis of variance were used to test differences in demographics and comorbidity distribution among tertiles of the targeted pollutants. Before controlling for multiple pollutants, hazard ratios for the overall population were 19.88 (95% CI: 17.56-22.50) at 0.51-ppm increases in THC and 4.33 (95% CI: 3.97-4.73) at 0.27-ppm increases in NMHC. The highest adjusted hazard ratios for different multiple pollutant models of each targeted pollutant were statistically significant (all p values were </=0.05) for all patients at 29.67 (95% CI: 25.57-34.42) for THC and 16.24 (95% CI: 14.14-18.65) for NMHC. Our findings suggest that long-term exposure to THC and NMHC contribute to RVO development.
    Date: 2019-09-24
    Relation: PLoS ONE. 2019 Sep 24;14(9):Article number e0222895.
    Link to: http://dx.doi.org/10.1371/journal.pone.0222895
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1932-6203&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000532307700031
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85072616458
    Appears in Collections:[Chao A. Hsiung] Periodical Articles
    [Chi-Pang Wen(2001-2010)] Periodical Articles

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