國家衛生研究院 NHRI:Item 3990099045/12144

NHRI > Institute of Population Health Sciences > Chi-Pang Wen(2001-2010) > Conference Papers/Meeting Abstract > Item 3990099045/12144

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/12144

Title:	"Smoking Paradox" in stroke survivors? Uncovering the truth from a national stroke registry data
Authors:	Wen, CP;Wang, HK;Hsu, CY
Contributors:	Institute of Population Health Sciences
Abstract:	Objective: Smokers with stroke were reported to have a better survival than nonsmokers, and this phenomenon was labeled as “smoking paradox”. This study is to assess its validity from a national stroke registry data. Methods: A total of 88,925 cases of stroke registered in the nationwide stroke registry system of Taiwan between 2006 and 2016, with 4,169 deaths, were analyzed. Age-specific mortality rate for current, ex- and non-smokers were calculated. NIHSS score (National Institutes of Health Stroke Scale) was measured at 3 months and 6 months Cox model was used to compare complications, mortality and outcomes between smoker and non-smoker ground. Results: Smokers constituted more than half of the men (55%) but only 5% of the women. The median age for current smokers was 60.2, for nonsmokers, 71.6, and for ex-smokers, 72.5. Smokers, with nearly 12 years younger than nonsmokers, had smaller mortality rate at younger age groups with fewer deaths, but much larger mortality after age 60, and doubled the mortality rate at the largest group after age 70. Smokers, who quit early, had similar outcome as nonsmokers. When age was controlled, current smokers had worse functional outcome (NIHSS) even at 3 months (adjusted OR, 1.08; 95% CI, 1.02-1.14). Conclusion: Smokers, but not ex-smokers, developed stroke 12 years younger than nonsmokers, an ominous sign for smokers. They had higher age-specific mortality rate and poorer outcome than nonsmokers. Quitting early nearly reversed the harms. Smoking paradox does not exist.
Date:	2019-02
Relation:	Stroke. 2019 Feb;50(Suppl. 1):Abstract number TP510.
Link to:	https://doi.org/10.1161/str.50.suppl_1.TP510
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0039-2499&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000478733401246
Appears in Collections:	[Chi-Pang Wen(2001-2010)] Conference Papers/Meeting Abstract

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