國家衛生研究院 NHRI:Item 3990099045/12132
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12189/12972 (94%)
造訪人次 : 956803      線上人數 : 844
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/12132


    題名: Association between prenatal exposure to PM2.5 and atopic eczema in Asian school-age children
    作者: Huang, H;Tsai, S;Wu, C;Tsai, H;Yao, T
    貢獻者: Institute of Population Health Sciences
    摘要: Background : Atopic eczema is a common inflammatory skin disease occurred in infants and children. Associations between ambient particulate matter < 2.5 μm (PM 2.5 ) and allergic diseases have been suggested in previous epidemiologic studies. However, limited cohort studies have examined the role of prenatal exposure to PM 2.5 plays in the development of childhood eczema. We aimed to evaluate whether prenatal exposure to PM 2.5 was associated with eczema in a cohort of Asian school- age children. Method : The study consists of 1169 full- term (≥37 weeks of gestation) school- aged children, part of the Longitudinal Investigation of Global Health in Taiwanese Schoolchildren (LIGHTS) cohort. Data related to clinical symptoms and physician- diagnosed eczema, and other pertinent demographic/ epidemiologic factors were collected using a modified International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. Children with atopy were defined based on Phadiatop Infant test (≥ 0.35 PAU/L). Prenatal exposure to PM 2.5 levels were estimated by linking their residential addresses during prenatal stage to air quality monitoring stations operated by Taiwan Air Quality Monitoring Network (TAQMN). Multiple logistic regressions with covariates adjustment were carried out to examine the association of prenatal exposure to PM 2.5 with physiciandiagnosed eczema. Results : There were 426 (36.4%) children with physiciandiagnosed eczema. The risk of physician- diagnosed eczema was increased with higher exposure to PM 2.5 during entire pregnancy (adjusted odds ratio (AOR) = 1.07, 95% confidence interval: 1.01- 1.13). Particularly, higher exposure to PM 2.5 in the second trimester (AOR = 1.04, 95% CI: 1.01- 1.08), but not first or third trimesters, significantly increased the risk of physician- diagnosed eczema. In addition, results from stratified analysis suggested that exposure to PM 2.5 during entire pregnancy was positively associated with physician- diagnosed eczema among children with atopy (AOR = 1.12, 95% CI:1.04- 1.21), but not among those without atopy. In the second trimester, risk of physician- diagnosed eczema associated with PM2.5 among children with atopy (AOR = 1.05, 95% CI:1.01- 1.09) was higher than those without atopy (AOR = 1.03, 95% CI:0.97- 1.09). Conclusion : This study shows that prenatal exposure to PM 2.5 was positively associated with atopic eczema in Asian school- age children.
    日期: 2019-08
    關聯: Allergy. 2019 Aug;74(S106):604-605.
    Link to: https://doi.org/10.1111/all.13961
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0105-4538&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000480254004011
    顯示於類別:[蔡慧如] 會議論文/會議摘要

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    ISI000480254004011.pdf1576KbAdobe PDF648檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋