國家衛生研究院 NHRI:Item 3990099045/12099
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    题名: Seeing better and going deeper in cancer nanotheranostics
    作者: Sivasubramanian, M;Chuang, YC;Chen, NT;Lo, LW
    贡献者: Institute of Biomedical Engineering and Nanomedicine
    摘要: Biomedical imaging modalities in clinical practice have revolutionized oncology for several decades. State-of-the-art biomedical techniques allow visualizing both normal physiological and pathological architectures of the human body. The use of nanoparticles (NP) as contrast agents enabled visualization of refined contrast images with superior resolution, which assists clinicians in more accurate diagnoses and in planning appropriate therapy. These desirable features are due to the ability of NPs to carry high payloads (contrast agents or drugs), increased in vivo half-life, and disease-specific accumulation. We review the various NP-based interventions for treatments of deep-seated tumors, involving "seeing better" to precisely visualize early diagnosis and "going deeper" to activate selective therapeutics in situ.
    日期: 2019-07-16
    關聯: International Journal of Molecular Sciences. 2019 Jul 16;20(14):Article number 3490.
    Link to: http://dx.doi.org/10.3390/ijms20143490
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1422-0067&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000480449300114
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85070100677
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