國家衛生研究院 NHRI:Item 3990099045/1132

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Title:	A modified Robinson annulation process to alpha,alpha-disubstituted-beta,gamma-unsaturated cyclohexanone system. Application to the total synthesis of nanaimoal
Other Titles:	A modified Robinson annulation process to α,α-disubstituted-β,γ-unsaturated cyclohexanone system. Application to the total synthesis of nanaimoal
Authors:	Liu, HJ;Ly, TW;Tai, CL;Wu, JD;Liang, JK;Guo, JC;Tseng, NW;Shia, KS
Contributors:	Division of Biotechnology and Pharmaceutical Research
Abstract:	4-Cyano-2-cyclohexenones were found to be susceptible to reductive alkylation reactions, giving the corresponding 2,2-disubstituted-3-cyclohexenone derivatives in a completely regioselective manner. This newly developed methodology has been successfully applied towards the total synthesis, in racemic form, of the marine natural product nanaimoal. (C) 2003 Elsevier Science Ltd. All rights reserved.
Keywords:	Chemistry, Organic
Date:	2003-02-17
Relation:	Tetrahedron. 2003 Feb;59(8):1209-1226.
Link to:	http://dx.doi.org/10.1016/S0040-4020(03)00034-6
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0040-4020&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000181019900010
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0037450403
Appears in Collections:	[Kak-Shan Shia] Periodical Articles

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