國家衛生研究院 NHRI:Item 3990099045/11133
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    題名: Increasing trends of anaphylaxis-related events: An analysis of anaphylaxis nationwide data in Taiwan, 2001-2013
    作者: Yao, TC;Huang, YW;Wu, HT;Tsai, YT;Wang, JY;Tsai, HJ
    貢獻者: Institute of Population Health Sciences
    摘要: RATIONALE: Anaphylaxis is a severe, potentially fatal, and systemic allergic reaction. Previous studies document increasing trends in the incidence and rates of anaphylaxis-related events in Western countries; however, few studies have been reported in Asian countries. We aimed to determine trends in incident rates of anaphylaxis-related events in Taiwan from 2001 through 2013. METHODS: We utilized medical claims data from the National Health Insurance Research Database in Taiwan. We identified anaphylaxis-related events and calculated incident rates, accordingly. Regression-based analyses were applied to examine trends and incident rates across study years. RESULTS: A total of 2,496 patients with first-time anaphylaxis were identified. The mean (standard deviation) age was 45.11 (20.64) years, and 56% of patients were male. The overall incident rate of anaphylaxis-related outpatient events was 6.94 (95% CI 5 6.77-7.22) per 100,000 person-years. When stratifying by age, significant increasing incident rates were observed among subjects aged < 18, 19-39, and 40-59 years (all p _ trend < 0.01), but not among subjects aged > 60 years. Among 2,496 patients, 1,696 (68.0%) patients were identified only from outpatient or emergency department (ED) visits, 495 (19.8%) patients were hospitalized, and 305 (12.2%) hospitalized patients were admitted to intensive care units. Furthermore, time trend of anaphylaxis-related outpatient or ED visits has increased over time ( p _trend 5 0.01), but time trend of anaphylaxisrelated hospitalization has decreased over time ( p _trend < 0.01). CONCLUSIONS: In this study, we observed the increasing incident rate of anaphylaxis-related events over time. The increasing incident rates were associated with different age groups, but not among subjects aged > 60 years.
    日期: 2018-02
    關聯: Journal of Allergy and Clinical Immunology. 2018 Feb;141(2, Suppl.):AB153.
    Link to: https://doi.org/10.1016/j.jaci.2017.12.489
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0091-6749&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000429306700484
    顯示於類別:[蔡慧如] 會議論文/會議摘要

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