國家衛生研究院 NHRI:Item 3990099045/11095
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    题名: Life years lost and lifetime healthcare expenditures of stroke: A 14-year population-based cohort study in Taiwan
    作者: Lee, JH;Jeng, JS;Hwang, JS;Chang, YY;Wang, JD
    贡献者: National Institute of Environmental Health Sciences
    摘要: Background: Little is known about the long-term social and financial impact of stroke and its subtypes. Objective: We aimed to estimate life years lost, and lifetime direct medical costs of stroke by subtypes, gender and age groups. Patients and Methods/Material and Methods: We used populationbased claims data from the Taiwan National Health Insurance Research Database to establish the stroke cohort. Adult stroke patients hospitalized for the first time during 1998-2010 were recruited and followed up till 2011. Assuming a constant excess hazard, we extrapolated lifetime survival function after a 14-years of follow-up using a semi-parametric method. For each stroke patient, we simulated age- and gender-matched referents based on national vital statistics to estimate expected years of life loss. We calculated the mean monthly direct medical costs, which were multiplied with the survival probability of the cohort and summed up throughout life to estimate the lifetime healthcare expenditures. Results: A total of 377,116 ischemic stroke (IS), 114,560 intracerebral hemorrhage (ICH), and 18,525 subarachnoid hemorrhage (SAH) patients were included. The average EYLL was 5.65 years (95% confidence interval 5.42~5.88), and SAH patients had the highest EYLL (10.6 years), followed by ICH (9.13 years) and IS (5.34 years). The estimated average LTHE per case for ICH and IS were USD 33,588 and 32,367, respectively. Stroke with younger onset was associated with higher LTHE with the highest in young females with ICH. Conclusion: The ICH would result in greater life years lost than that of IS with similar direct medical costs. Stroke in young adults was associated with greater EYLL and higher LTHE.
    日期: 2017-10
    關聯: Journal of the Neurological Sciences. 2017 Oct;381(Suppl. S):880.
    Link to: http://dx.doi.org/10.1016/j.jns.2017.08.2480
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0022-510X&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000427450303344
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