We identified 20-22 resistance genes, carried in four incompatibility groups of plasmid, in each of five genetically closely-related Salmonella enterica serovar Typhimurium strains recovered from humans, pigs, and chicken. The genes conferred resistance to aminoglycosides, chloramphenicol, sulfonamides, trimethoprim, tetracycline, fluoroquinolones, extended-spectrum cephalosporins and cefoxitin, and azithromycin. This study demonstrates the transmission of multidrug-resistant Salmonella strains among humans and food animals and may be the first identification of mphA in azithromycin-resistant Salmonella strains in Taiwan.
Date:
2018-05
Relation:
Antimicrobial Agents and Chemotherapy. 2018 May;62(5):Article number e00213-18.