國家衛生研究院 NHRI:Item 3990099045/11061

NHRI > National Institute of Infectious Diseases and Vaccinology > Ming-Hsi Huang > Patents > Item 3990099045/11061

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Title:	用於穩定油包水乳液及控制釋放生物活性物質之山梨醇酐聚酯複合體
Authors:	Huang, MH;Huang, CY;Chong, PCS;Leng, CH;Liu, SJ;Chen, HW
Contributors:	National Institute of Infectious Diseases and Vaccinology
Abstract:	本發明揭示一種在水包油包水(W/O/W)乳液中之組合物，其組成成分包括：(a)含H2O成分之連續水相；(b)分散在連續水相間之油相或油殼；以及(c)用於穩定連續水相和油相(或油殼)界面之親水性聚合物，使其形成水包油(O/W)乳液。油相或油殼包括：(i)油、(ii)分散在油或油殼內之內部水相，以及(iii)一親脂性山梨醇酐-聚酯複合體，可穩定油和內部水相之間的界面，以形成油包水(W/O)乳液。該親脂性山梨醇酐-聚酯複合體包含：(1)山梨醇酐，以及(2)複合到山梨醇酐上之丙交酯-己內酯共聚物或聚乳酸。 A composition in a water-in-oil-in-water (W/O/W) emulsion is disclosed. The composition comprises: (a) a continuous aqueous phase, comprising H2O; (b) an oil phase or an oil shell, dispersed in the continuous aqueous phase; and (c) a hydrophilic polymer, stabilizing an interface between the continuous aqueous phase and the oil phase or the oil shell to form an oil-in-water (O/W) emulsion. The oil phase or the oil shell comprises: (i) oil; (ii) an internal aqueous phase, dispersed within the oil or the oil shell; and (iii) a lipophilic sorbitan-polyester conjugate, stabilizing an interface between the oil and the inner aqueous phase to form a water-in-oil (W/O) emulsion. The lipophilic sorbitan-polyester conjugate comprises: (1) sorbitan; and (2) poly(lactide-co- ε -caprolactone) or polylactic acid (polylactide), conjugated to the sorbitan.
Date:	2017-09
Relation:	I598114/2017-09-11
Link to:	https://twpat1.tipo.gov.tw/tipotwoc/tipotwkm?!!FR_I598114
Appears in Collections:	[Ming-Hsi Huang] Patents [Pele Choi-Sing Chong] Patents [Chih-Hsiang Leng] Patents [Shih-Jen Liu] Patents [Hsin-Wei Chen] Patents

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