國家衛生研究院 NHRI:Item 3990099045/10545
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    题名: modPhEA: model organism Phenotype Enrichment Analysis of eukaryotic gene sets
    作者: Weng, MP;Liao, BY
    贡献者: Division of Biostatistics and Bioinformatics
    摘要: Motivation: Genome-scale phenotypic data are available for many model organisms, yet existing tools to functionally interpret gene sets from these phenotypic data are largely based on mutagenesis-derived phenotypes observed in mouse or human. Results: Data from both mutagenesis and knockdown experiments are incorporated into mod PhEA to allow users to perform enrichment analyses based on phenotypes observed in budding yeast ( Saccharomyces cerevisiae ), roundworm ( Caenorhabditis elegans ), fruit fly ( Drosophila melanogaster ), zebrafish ( Danio rerio ), mouse ( Mus musculus ), and humans ( Homo sapiens ). The phenotypes analyzed can be customized to investigate complex traits and gene sets from any fully sequenced animal or fungal genome are also supported by mod PhEA.
    日期: 2017-11
    關聯: Bioinformatics. 2017 Nov;33(21):3505-3507.
    Link to: http://dx.doi.org/10.1093/bioinformatics/btx426
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1367-4803&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000413645800031
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85050202424
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