國家衛生研究院 NHRI:
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    日期题名關聯
    2020-08 BPR6K609: An Aurora kinase inhibitor targeting small cell lung cancer with MYC amplification Cancer Research. 2020 Aug;80(16):1937.
    2019-10 Inhibition of Rspo-Wnt pathway facilitates checkpoint blockade therapy by anti-RSPO3 antibody (DBPR117) Annals of Oncology. 2019 Oct;30(Suppl. 5):191.
    2019-07 BPRDP056, a novel small molecule drug conjugate specifically targeting phosphatidylserine for cancer therapy Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 227.
    2019-07 Use of integrated genomic analyses in patient-derived tumor model to discover new clinical indications for the multikinase inhibitor drug candidate, DBPR216 Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 4626.
    2019-07 An Aurora kinase inhibitor BPR6K471 inhibits tumor growth and reduces the cancer stem cell-like properties of small cell lung cancer Cancer Research. 2019 Jul;79(13, Suppl.):Abstract number 3851.
    2018-12 Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer Cancer Science. 2018 Dec;109(SI, Suppl. 2):210.
    2018-12 Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer Cancer Science. 2018 Dec;109(Suppl. 2, SI):1257.
    2018-07 4-Bromophenylhydrazinyl benzenesulfonylphenylureas inhibit indoleamine 2,3-dioxygenase in vitro and in vivo Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 1664.
    2018-01 Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer Cancer Science. 2018 Jan;109(Suppl. 1):739.
    2017-04 Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482.
    2016-12 Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P.
    2016-10 Multifunctional nanoparticles for oral protein drug delivery Diabetes Research and Clinical Practice. 2016 Oct;120(Suppl. 1):S19.
    2016-08 Dipeptidyl peptidase-4 inhibitor LAF-237 improves glucose tolerance and expends graft beta cell mass in diabetic mice transplanted with a sufficient number of islets Diabetologia. 2016 Aug;59(Suppl. 1):S198.
    2016-02 Multifunctional nanoparticles for oral protein drug delivery Nanomedicine: Nanotechnology, Biology and Medicine. 2016 Feb;12(2):463.
    2015-08 Zinc-dipicolylamine directed pharmaceutical delivery system (ZAPS) as an innovative cancer drug delivery platform Cancer Research. 2015 Aug;75(Suppl. 15):Abstract number 4413.
    2015-08 Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 490.
    2014-11 Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent European Journal of Cancer. 2014 Nov;50(Suppl. 6):92-93.
    2014-10 YYEI motif is critical to oncogenicity of 14-3-3 proteins Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 3527.
    2014-10 Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 1756.
    2014-03 DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 315-MEDI.
    2013-11 A development drug candidate targeting EGFR kinase for lung cancer: DBPR112 Journal of Thoracic Oncology. 2013 Nov;8(Suppl. 2):S779-S780.
    2013-04-07 BPR000K, a novel Aurora kinase inhibitor Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI.
    2013-04-07 Development drug candidate targeting EGFR kinase: DBPR112 Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 299-MEDI.
    2013-04 Design and synthesis of Aurora kinase inhibitors as anticancer agents Abstracts of Papers - American Chemical Society. 2013 Apr;245:Article number 301-MEDI.
    2012-11 BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia European Journal of Cancer. 2012 Nov;48(Suppl. 6):53-54.

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