國家衛生研究院 NHRI:Item 3990099045/10072
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 12145/12927 (94%)
造访人次 : 861836      在线人数 : 806
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    主页 ‧ 登入 ‧ 上传 ‧ 说明 ‧ 关于NHRI ‧ 管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/10072


    题名: BMI and stroke mortality: Is there an obesity paradox among Asians?
    作者: Wu, MH;Hsu, CY;Tsao, CK;Lu, PJ;Lee, JH;Tsai, SP;Wen, CP
    贡献者: Division of Health Services and Preventive Medicine
    摘要: Background and Rationale: Overweight and obesity were progressively associated with increased ischemic stroke, in a meta-analysis pooling 25 studies. However, ‘obesity paradox’ was also reported for stroke in that obesity or overweight was protective of stroke. Across the spectrum of Body Mass Index (BMI), ‘who has the most risk’ remains unclear, when major risk factors were controlled. Methods: A large cohort from Taiwan, N = 469,088, successively recruited during 1994–2008 with comprehensive health screening data, was followed up with National Death file. Stroke risks for underweight (BMI <18.5), overweight (BMI25-29) and obesity (BMI ≥30) were expressed as hazard ratios (HR) by Cox model with BMI 23–24 as reference. Stroke as a whole or ischemic and hemorrhagic stroke separately were analyzed. Results: Underweight had the highest stroke mortality (HR = 1.90, 95% CI: 1.35–2.67), followed by next underweight with BMI at 18.5–22 (HR = 1.25, 95% CI: 1.03–1.52), while overweight (HR = 0.95, 95% CI: 0.78–1.16) and obesity (HR = 1.00, 95% CI: 0.70–1.43) showed no stroke increase. Among three age groups with underweight, age 40–64 had highest risk with HR = 2.71 (95% CI: 1.5–4.8). Significant results for underweight were similar for smokers (HR = 1.83, 95% CI: 1.02–3.27) or nonsmokers (HR = 2.03, 95% CI: 1.33–3.09), for hypertension (HR = 1.76; 95% CI: 1.13–2.72) or no hypertension (HR = 3.37; 95% CI: 1.88–6.06), and for ischemic stroke (HR: 1.82; 95% CI:1.15–2.89) or for hemorrhagic stroke (HR = 1.90: 95% CI: 1.15–3.14). Conclusion: In this large Asian cohort, for stroke mortality, all groups with underweight (BMI <18.5) had the highest risk, particularly at middle-aged adults (40–64). Obesity, defined as BMI ≥30, showed no increase in risk nor protective power against stroke.
    日期: 2016-07
    關聯: Cerebrovascular Diseases. 2016 Jul;42(Suppl. 1):21.
    Link to: http://dx.doi.org/10.1159/000447732
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1015-9770&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000381107200042
    显示于类别:[溫啟邦(2001-2010)] 會議論文/會議摘要

    文件中的档案:

    档案 描述 大小格式浏览次数
    ISI000381107200042.pdf112KbAdobe PDF423检视/开启


    在NHRI中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈