國家衛生研究院 NHRI:Item 3990099045/10064
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/10064


    Title: Circulating 25-hydroxyvitamin D and physical performance in older adults: A nationwide study in Taiwan
    Authors: Chuang, SC;Chen, HL;Tseng, WT;Wu, IC;Hsu, CC;Chang, HY;Chen, YI;Lee, MM;Liu, K;Hsiung, CA
    Contributors: Division of Biostatistics and Bioinformatics;Division of Health Services and Preventive Medicine;Division of Geriatric Research;Division of Health Policy Translation
    Abstract: BACKGROUND: A previous study indicated that 31% of the elderly in Taiwan have a vitamin D deficiency. Vitamin D adequacy has been associated with physical performance in the elderly. OBJECTIVES: The first aim of the current study was to identify the determinants for vitamin D deficiency. The second aim was to evaluate the association between vitamin D status and physical performance. DESIGN: A total of 5664 community-dwelling participants aged >/=55 y were recruited since 2008. Plasma total 25-hydroxyvitamin D concentrations were originally determined by ELISA and calibrated to a chemiluminescence measurement. Physical performance was assessed by handgrip strength, the Short Physical Performance Battery, timed up and go, a 6-min walk test, and single-leg stands. Multiple linear regression and logistic regression were used to estimate the cross-sectional associations. RESULTS: Vitamin D inadequacy (<50 nmol/L) was related to higher education (P-trend < 0.01), body mass index [(BMI; in kg/m2) ORs (95% CIs) for >/=30 compared with 18.5 to <25 were 1.78 (1.14, 2.78) for men and 1.53 (1.11, 2.11) for women], and vegetable intake [fourth compared with first quartile, 1.58 (1.15, 2.18) for men and 2.38 (1.82, 3.12) for women]. Higher intakes of fish [fourth compared with first quartile, 0.44 (0.33, 0.59) for men and 0.27 (0.21, 0.36) for women] and milk [fourth compared with first quartile, 0.46 (0.31, 0.69) for men and 0.69 (0.49, 0.95) for women] were associated with lower risk of vitamin D inadequacy. Few subjects had 25-hydroxyvitamin D concentrations <30 nmol/L. Above that concentration, there was no dose-effect relation with physical performance except for single-leg stands. CONCLUSIONS: The factors associated with vitamin D inadequacy in Taiwan were higher education, higher BMI, and lower fish and milk intakes. No dose-effect relation existed between vitamin D concentration and physical performance except for single-leg stands.
    Date: 2016-10-12
    Relation: American Journal of Clinical Nutrition. 2016 Oct 12;104(5):1334-1344.
    Link to: http://dx.doi.org/10.3945/ajcn.115.122804
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0002-9165&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000386994500020
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84994335510
    Appears in Collections:[Chao A. Hsiung] Periodical Articles
    [Hsing-Yi Chang] Periodical Articles
    [I-Chien Wu] Periodical Articles
    [Shu-Chun Chuang] Periodical Articles
    [Chih-Cheng Hsu] Periodical Articles

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