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    Items for Author "Lee, SJ" 

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    Showing 102 items.

    Collection Date Title Relation Bitstream
    [李秀珠] 期刊論文 2024-02-15 Vitamin B12 inhibits peptidylarginine deiminases and ameliorates rheumatoid arthritis in CAIA mice -
    [李秀珠] 期刊論文 2023-07-20 Natural fucoidans inhibit coronaviruses by targeting viral spike protein and host cell furin -
    [李秀珠] 期刊論文 2023-01-19 The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b [Erratum:Pharmaceutics. 2022 Jul 21;14(7):Article number 1511.] -
    [李秀珠] 期刊論文 2022-07-21 The synergistic inhibition of coronavirus replication and induced cytokine production by ciclesonide and the tylophorine-based compound dbq33b -
    [李秀珠] 期刊論文 2022-02-17 Tyrphostin AG1024 suppresses coronaviral replication by downregulating JAK1 via an IR/IGF-1R independent proteolysis mediated by Ndfip1/2_NEDD4-like E3 ligase itch -
    [李秀珠] 期刊論文 2021-08-13 Remdesivir and cyclosporine synergistically inhibit the human coronaviruses OC43 and SARS-CoV-2 -
    [李秀珠] 期刊論文 2020-12-14 Inhibition of SARS-CoV-2 by highly potent broad-spectrum anti-coronaviral tylophorine-based derivatives -
    [李秀珠] 期刊論文 2020-12 Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na(+)/K(+)-ATPase independent proteolysis[Erratum:Biochemical Pharmacology. 2020 Oct;180:Article number 114122.] -
    [李秀珠] 期刊論文 2020-10 Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na(+)/K(+)-ATPase independent proteolysis -
    [徐祖安] 期刊論文 2020-08-20 Discovery of M protease inhibitors encoded by SARS-CoV-2 -
    [李秀珠] 期刊論文 2020-08 Polyketide synthase gene expression in relation to chloromonilicin and melanin production in Monilinia fructicola -
    [陳炯東] 期刊論文 2020-08 Artificial intelligence approach fighting COVID-19 with repurposing drugs -
    [李秀珠] 期刊論文 2020-08 Repurposing old drugs as antiviral agents for coronaviruses -
    [李秀珠] 期刊論文 2020-02 The cardenolides ouabain and reevesioside A promote FGF2 secretion and subsequent FGFR1 phosphorylation via converged ERK1/2 activation -
    [李秀珠] 期刊論文 2020-02 Tylophorine-based compounds are therapeutic in rheumatoid arthritis by targeting the caprin-1 ribonucleoprotein complex and inhibiting expression of associated c-Myc and HIF-1alpha -
    [李秀珠] 期刊論文 2019-08-06 Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: An identification of a novel oncotarget[Erratum: Oncotarget. 2015 Feb;6(4):2148-2163.] -
    [李秀珠] 期刊論文 2018-10 The cardenolide ouabain suppresses coronaviral replication via augmenting a Na(+)/K(+)-ATPase-dependent PI3K_PDK1 axis signaling -
    [李秀珠] 期刊論文 2017-10 Identification of anti-viral activity of the cardenolides, Na+/K+-ATPase inhibitors, against porcine transmissible gastroenteritis virus -
    [李秀珠] 期刊論文 2017-07 Design, synthesis, and evaluation of thiazolidine-2,4-dione derivatives as a novel class of glutaminase inhibitors -
    [李秀珠] 期刊論文 2017-06-22 Targeting coronaviral replication and cellular JAK2 mediated dominant NF-kappaB activation for comprehensive and ultimate inhibition of coronaviral activity -
    [李秀珠] 期刊論文 2017-05-22 Bioactive composition of Reevesia formosana root and stem with cytotoxic activity potential -
    [熊昭] 期刊論文 2017-05 Association analyses of East Asian individuals and trans-ancestry analyses with European individuals reveal new loci associated with cholesterol and triglyceride levels -
    [李秀珠] 期刊論文 2016-10 Cytotoxic cardenolides and sesquiterpenoids from the fruits of Reevesia formosana -
    [李秀珠] 會議論文/會議摘要 2016-04 Discovery and development of tylophorine derived dibenzoquinolines-33b compounds into therapeutic agents -
    [李秀珠] 期刊論文 2015-07 Biological evaluation of secondary metabolites from the root of machilus obovatifolia -
    [李秀珠] 會議論文/會議摘要 2015-04 Tylophorine compounds exert anti-cancer activity by targeting a ribonucleoprotein complex containing caprin-1 and c-Myc mRNA -
    [李秀珠] 期刊論文 2015-02 Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: An identification of a novel oncotarget -
    [李秀珠] 會議論文/會議摘要 2014-11 Chemical constituents and cytotoxic activities from the fruits of Reevesia formosana -
    [李秀珠] 會議論文/會議摘要 2014-11 Chemical constituents and cytotoxic activities from the root and the stem of Reevesia formosana -
    [李秀珠] 期刊論文 2014-08 Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells -
    [李秀珠] 專利 2014-05-11 二苯並〔f,h〕異喹啉衍生物及其醫藥組成物 -
    [李秀珠] 專利 2014-03-21 菲并吲哚啶類似物 -
    [岳嶽] 期刊論文 2014-01 A novel dengue virus inhibitor, BP13944, discovered by high-throughput screening with dengue virus replicon cells selects for resistance in the viral NS2B/NS3 protease -
    [李秀珠] 專利 2013-07-16 Dibenzo[f,h]isoquinoline derivatives -
    [李秀珠] 期刊論文 2013-06 c-Jun-mediated anti-cancer mechanisms of tylophorine -
    [李秀珠] 報告 2013-05-14 Phenanthroindolizidine analogues -
    [李秀珠] 會議論文/會議摘要 2013-04-13 Exploration of the role of tylophorine E ring in anti-Coronavirus activity-Tylophorine derived dibenzoquinolines impart multi-biological activities as orally active agents -
    [李秀珠] 會議論文/會議摘要 2013-04 Tylophorine induces c-Jun protein accumulation through two discrete prolonged pathways NF-kappaB/PKCdelta/JNK and PI3K/PDK1/PP2A/eEF2 to promote G1 arrest in carcinoma cells -
    [李秀珠] 會議論文/會議摘要 2013-04 Identification of a quinone compound inhibits human glutaminase activity and induces autophagy in carcinoma cells -
    [李秀珠] 期刊論文 2013-03 Cytotoxic cardenolide glycosides from the root of Reevesia formosana -
    [葉燈光] 期刊論文 2012-12-13 Synthesis and biological evaluation of tylophorine-derived dibenzoquinolines as orally active agents: Exploration of the role of tylophorine e ring on biological activity -
    [李秀珠] 期刊論文 2011-11 Isolation and biological activities of phenanthroindolizidine and septicine alkaloids from the formosan tylophora ovata -
    [趙宇生(2002-2013)] 期刊論文 2011-01 Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay -
    [李秀珠] 期刊論文 2011-01 Antitubercular resorcinol analogs and benzenoid C-glucoside from the roots of ardisia cornudentata -
    [趙宇生(2002-2013)] 期刊論文 2010-11 Identification of phenanthroindolizines and phenanthroquinolizidines as novel potent anti-coronaviral agents for porcine enteropathogenic coronavirus transmissible gastroenteritis virus and human severe acute respiratory syndrome coronavirus -
    [李秀珠] 期刊論文 2010-11 Cytotoxic Sesquiterpenes from Magnolia kachirachirai -
    [李秀珠] 專利 2010-10-11 乙烯磺酸鹽化合物 -
    [李秀珠] 期刊論文 2010-09 Cytotoxic flavonoids from the leaves of cryptocarya chinensis -
    [杜鴻運] 期刊論文 2010-08 High prevalence of latent tuberculosis infection in dialysis patients using the interferon-{gamma} release assay and tuberculin skin test -
    [李秀珠] 期刊論文 2010-04-20 A new butanolide and a new secobutanolide from Litsea lii var. nunkao-tahangensis -
    [李秀珠] 專利 2010-01-26 Phenanthroindolizidine alkaloids -
    [李秀珠] 期刊論文 2009-12 Cytotoxic alkyl benzoquinones and alkyl phenols from Ardisia virens -
    [李秀珠] 期刊論文 2009-12 Antitubercular resorcinols and cytotoxic alkyl benzoquinones from Ardisia kusukuensis -
    [李秀珠] 專利 2009-10-07 Benzothiazolium compounds for use in methods of inhibiting NO production and TNF alpha and treating coronaviral infection -
    [李秀珠] 期刊論文 2009-08-14 Tylophorine arrests carcinoma cells at G1 phase by downregulating cyclin A2 expression -
    [李秀珠] 會議論文/會議摘要 2009-07 Additional new 5,6-dihydroflavanones and cytotoxic constituents from the leaves of Cryptocarya chinensis -
    [李秀珠] 期刊論文 2009-06 Secondary metabolites and cytotoxic activities from the stem bark of Zanthoxylum nitidum -
    [伍素瑩] 期刊論文 2009-06 A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitiors [Erratum: European Journal of Medicinal Chemistry. 2008 Aug;43(8):1603-1611.] -
    [李秀珠] 專利 2009-02-21 苯噻唑離子化合物 -
    [李秀珠] 期刊論文 2008-10-15 Analogues of 2-phenyl-ethenesulfonic acid phenyl ester have dual functions of inhibiting expression of inducible nitric oxide synthase and activating peroxisome proliferator-activated receptor gamma -
    [伍素瑩] 期刊論文 2008-08 A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors -
    [李秀珠] 會議論文/會議摘要 2008-07 Chemical constituents and cytotoxic activity of the root of Antidesma hiiranense -
    [李秀珠] 會議論文/會議摘要 2008-07 Chemical constituents from a cytotoxic root extract of Anneslea lanceolata -
    [李秀珠] 會議論文/會議摘要 2008-07 Secondary metabolites and cytotoxic activity of the stem bark of Litsea akoensis -
    [李秀珠] 會議論文/會議摘要 2008-07 Chemical constituents and cytotoxic activity of the root wood of Magnolia kachirachirai -
    [李秀珠] 期刊論文 2008-06 Cytotoxic constituents from the root wood of formosan Michelia compressa -
    [李秀珠] 專利 2008-02-19 Phenanthroindolizidine alkaloids -
    [李秀珠] 期刊論文 2008 Secondary metabolites from the stem bark of Litsea akoensis and their cytotoxic activity -
    [李秀珠] 期刊論文 2008 Secondary metabolites from the leaves of Litsea lii var. nunkao-tahangensis -
    [李秀珠] 會議論文/會議摘要 2007-12 Tylophorine elevates the amounts of c-Jun protein in carcinoma cells -
    [李秀珠] 專利 2007-11-21 丹參酮吲哚啶生物鹼 -
    [李秀珠] 期刊論文 2007-11 Novel small-molecule inhibitors of transmissible gastroenteritis virus -
    [李秀珠] 期刊論文 2007-10 Chemical Constituents from the root of Antidesma pentandrum var. barbatum -
    [李秀珠] 會議論文/會議摘要 2007-04-18 Identification of novel small-molecule inhibitors of transmissible gastroenteritis virus -
    [李秀珠] 期刊論文 2007-04 Biphenyls from Pourthiaea lucida -
    [李秀珠] 期刊論文 2007-03-23 Anti-inflammatory effects of 7-methoxycryptopleurine and structure-activity relations of phenanthroindolizidines and phenanthroquinolizidines -
    [李秀珠] 會議論文/會議摘要 2007-02 Anti-inflammatory effects of 7-methoxyl-cryptopleurine and structure-activity relationships of phenanthroindolizidines and phenanthroquinolizidine -
    [蕭金福] 期刊論文 2007 Mixed noninferiority margin and statistical tests in active controlled trials -
    [李秀珠] 期刊論文 2006-06 Synthesis and cytotoxicity studies of cyclohepta[b]indoles, benzo[6,7]cyclohepta[1,2-b]indoles, indeno[1,2-b]indoles, and benzo[a]carbazoles -
    [李秀珠] 會議論文/會議摘要 2006-04 Analysis of the structure-activity relationships between phenanthroindolizidines and phenanthroquinolizidines -
    [李秀珠] 期刊論文 2006-03 Anti-inflammatory mechanisms of phenanthroindolizidine alkaloids -
    [蔣維棠] 期刊論文 2006-01-12 2-[3-[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]-1,2,3,4-tetrahydroisoquinoline: A potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV -
    [李秀珠] 期刊論文 2006 Expedient synthesis and structure-activity relationships of phenanthroindolizidine and phenanthroquinolizidine alkaloids -
    [李秀珠] 期刊論文 2005-10-15 Synthesis, antiproliferative, and vasorelaxing evaluations of coumarin alpha-methylene-gamma-butyrolactones -
    [蔣維棠] 期刊論文 2005-07-01 Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors -
    [李秀珠] 期刊論文 2005-06-01 TEB4 is a C4HC3 RING finger-containing ubiquitin ligase of the endoplasmic reticulum -
    [李秀珠] 期刊論文 2005-05 Steryl epoxide, secobutanolide and butanolides from the stem wood of Machilus zuihoensis -
    [李秀珠] 期刊論文 2005-04-15 Benzothiazolium compounds: Novel classes of inhibitors that suppress the nitric oxide production in RAW264.7 cells stimulated by LPS/IFN gamma -
    [李秀珠] 會議論文/會議摘要 2005-04 The anti-inflammatory mechanisms of [Benzothiazol-Vinyl]-benzothiazolium compounds -
    [陳新(2002-2015)] 期刊論文 2005-02-01 Novel isoindoline compounds for potent and selective inhibition of prolyl dipeptidase DPP8 -
    [李秀珠] 會議論文/會議摘要 Tylophorine inhibits the expression of iNOS and COX-II through AP1 in RAW264.7 Cell Stimulated by LPS/IFNγ -
    [李秀珠] 期刊論文 2005 Effects of xenobiotics and peroxisome proliferator-activated receptor-alpha on the human UDPglucose dehydrogenase gene expression -
    [李秀珠] 會議論文/會議摘要 2004-09 Drug design of BPR0L075 as an anticancer agent -
    [謝興邦] 會議論文/會議摘要 2004-08-22 Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents -
    [謝興邦] 期刊論文 2004-08-12 Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents -
    [張俊彥] 期刊論文 2004-07-01 BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo -
    [李秀珠] 會議論文/會議摘要 2004-07 Drug design for BPR0L075 as an anticancer agent -
    [李秀珠] 會議論文/會議摘要 2004-05 Suppression of nitric oxide production in activated RAW264.7 cells by Phenanthroindolizidine alkaloids -
    [李秀珠] 期刊論文 2004-03 Cytotoxic and anti-HIV principles from the rhizomes of Begonia nantoensis -
    [李秀珠] 期刊論文 2004 Coumarinolignans from the root of Formosan Antidesma pentandrum var. barbatum -
    [李秀珠] 期刊論文 2003-07 Chemical and cytotoxic constituents from Peperomia sui -
    [李秀珠] 期刊論文 2003-04 Cytotoxic styrylpyrones from Goniothalamus amuyon -

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