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显示项目3571-3580 / 12972. (共1298页) << < 353 354 355 356 357 358 359 360 361 362 > >> 每页显示[10|25|50]项目

日期	题名	關聯
2013-11	Discovery and refinement of loci associated with lipid levels	Nature Genetics. 2013 Nov;45(11):1274-1283.
2014-08	Discovery and structure-activity relationships of phenyl benzenesulfonylhydrazides as novel indoleamine 2,3-dioxygenase inhibitors	Bioorganic and Medicinal Chemistry Letters. 2014 Aug;24(15):3403-3406.
2021-05-19	Discovery and synthesis of a pyrimidine-based aurora kinase inhibitor to reduce levels of MYC oncoproteins	Journal of Medicinal Chemistry. 2021 May 19;64(11):7312-7330.
2010-09	Discovery of 1-(2,4-Dichlorophenyl)-4-ethyl-5-(5-(2-(4-(trifluoromethyl)phenyl)ethynyl)thiophe n-2-yl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide as a potential peripheral cannabinoid-1 receptor inverse agonist	ChemMedChem. 2010 Sep;5(9):1439-1443.
2013-11-13	Discovery of 1-(2,4-Dichlorophenyl)-N-(piperidin-1-yl)-4-((pyrrolidine-1-sulfonamido)methyl)-5 -(5-((4-(trifluoromethyl)phenyl)ethynyl)thiophene-2-yl)-1H-pyrazole-3-carboxamide as a novel peripherally restricted cannabinoid-1 receptor antagonist with significant weight-loss efficacy in diet-induced obese mice	Journal of Medicinal Chemistry. 2013 Nov 13;56(24):9920-9933.
2015-08	Discovery of 2,4-diaminopyrimidines bearing a unique pharmacophore as anaplastic lymphoma kinase inhibitors	Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 182.
2009-07-23	Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice	Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4496-4510.
2013-06	Discovery of 3-phenyl-1H-5-pyrazolylamine derivatives containing a urea pharmacophore as potent and efficacious inhibitors of FMS-like tyrosine kinase-3 (FLT3)	Bioorganic and Medicinal Chemistry. 2013 Jun;21(11):2856-2867.
2008-07-24	Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors	Journal of Medicinal Chemistry. 2008 Jul;51(14):4351-4355.
2022-06-02	Discovery of a biomarker signature that reveals a molecular mechanism underlying diabetic kidney disease via organ cross talk	Diabetes Care. 2022 Jun 2;45(6):e102-e104.

显示项目3571-3580 / 12972. (共1298页) << < 353 354 355 356 357 358 359 360 361 362 > >> 每页显示[10|25|50]项目